
DeplinPRO Mood Health™ brings together four key nutrients in a multi-action formula that helps restore the biological balance needed for mood, stress, and cognitive function — supporting your ongoing depression care. It has over 15 years of clinical data and has helped millions of patients manage their depression. It directly supports individuals with MTHFR Gene Mutations, which inhibit the conversion of synthetic folic acid to usable folate, often aiding in the treatment of depressive symptoms. DeplinPRO Mood Health contains 15mg of L-Methylfolate, 2000 IU of Vitamin D3, 25mg of Zinc Bisglycinate and 250mg of L-Theanine.
Up to 70% of depressed patients have an MTHFR genetic mutation hindering folate conversion. L-methylfolate bypasses this, providing the active nutrient directly to the brain. MTHFR gene mutations (specifically C677T and A1298C) can lead to reduced production of neurotransmitters like serotonin, dopamine, and norepinephrine. This deficiency can negatively affect mood, contributing to depression, anxiety, bipolar disorder, ADHD, and chronic fatigue.
L-methylfolate (a bioavailable form of vitamin B9) aids mood by acting as a crucial cofactor in producing neurotransmitters that regulate emotions, including serotonin, dopamine, and norepinephrine.
Vitamin D3 and Zinc play essential, distinct roles in supporting brain health and mood regulation. Research suggests they work by modulating neurotransmitters, reducing brain inflammation, and supporting the growth and repair of neurons.
L-theanine has established anti-stress and anxiolytic (anxiety-reducing) properties. It acts within 30–40 minutes to create a calming effect. Studies also indicate that L-theanine can reduce depression-like symptoms and improve mood.
For more information on DeplinPRO Mood Health, visit deplin.com
DeplinPRO Mood Health may help Transcranial Magnetic Stimulation (TMS) work better by optimizing brain chemistry, specifically by increasing neurotransmitter production (serotonin, dopamine, norepinephrine) needed for positive treatment response. By correcting nutrient deficiencies, it may improve the efficacy of mental health treatments.

Below is a prescription request form. Please fill out the form completely and a prescription will be sent to Brand Direct Health Pharmacy within one business day. Please be sure to include your full name, DOB, phone and address to expedite your order.

Brand Direct Health Mail Order Pharmacy will reach out to you approximately one business day after you submit the form below. Your name and DOB will be required to verify your identity. BDH will gather your billing and verify shipping information.

If you don't receive a call within one business day, please reach out directly to BDH at (866) 331-6440.
(your phone may be blocking their call)

Your 3-Month Prescription of DeplinPRO is $195 plus shipping. To get $50 off your first fill, use coupon code "SAVE50DPL". (Only $145)
Be sure to note code, as it will be required. A monthly payment option is available if needed.

If after 90-Days, DeplinPRO Mood Health hasn't improved your mood health, BDH Pharmacy will give you a full refund on your prescription costs.

DeplinPRO is as safe as placebo and has no drug-to-drug interactions. It is taken once per day, with or without food, at a time convenient for you.
Begin your DeplinPRO journey today.
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